Ali Ashraf Mozafari; Mohammad Ali Mansournia; Kourosh Sayehmiri; Bahareh Ghiasi; Mehdi Yaseri; Golnaz Azami
Volume 22, Issue 7 , 2020
Abstract
Background: Lipid disorders are a well-documented risk factor for chronic kidney disease (CKD), but the impact of lipid abnormal- ities in the progression of the disease remains mixed.
Objectives: The current study aimed to extend the existing knowledge about the effect of lipid disorders in disease ...
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Background: Lipid disorders are a well-documented risk factor for chronic kidney disease (CKD), but the impact of lipid abnormal- ities in the progression of the disease remains mixed.
Objectives: The current study aimed to extend the existing knowledge about the effect of lipid disorders in disease progression from moderate to severe stage using Flexible parametric survival models.
Methods: This retrospective cohort study included 308 moderate CKD patients who received the nephrologist follow-up visits at the nephrology clinic, Ilam (Iran), from 2012 to 2019. The survival time was determined based on the time medically diagnosed with moderate stages (GFR = 59 - 55 mL/min per 1.73 m2) to the time of progression to the severe stage (GFR = 29 - 25 mL/min per 1.73 m2) hazard using flexible parametric survival models.
Results: In univariate analysis, high levels of TG, LDL, and cholesterol were important risk factors which affect the CKD progression. The hazard of patients with TG > 200 mg/dL was 1.69 times higher than patients with desirable TG levels (P = 0.09). Moreover, for patients with LDL > 160 mg/dL, the hazard was 2.12 times higher than patients with desirable LDL levels (P = 0.01). The hazard of patients with total cholesterol levels > 240 mg/dL was 2.10 times higher than patients with desirable cholesterol levels (P = 0.003). The adjusted model was shown to better fit the PH model. Cholesterol levels > 240 mg/dL remains a significant risk factor for CKD progression (P = 0.03).
Conclusions: Effective treatment programs should pay closer attention to screening and treatment of hyperlipidemia in patients diagnosed with moderate CKD.
Mahboubeh Bayat; Iraj Harirchi; Gholamhossein Salehi Zalani; Ali Akbari-Sari; Azad Shokri; Mahmoud Khodadost; S. Elmira Mirbahaeddin; Mehdi Yaseri; Ebrahim Jaafaripooyan
Volume 19, Issue 7 , July 2017, , Pages 1-8
Abstract
Background: Cancer is the third cause of death in Iran. Oncologists play a key role in declining the mortality rate of cancer.Objectives: This study aims to accurately estimate oncologists’ active supply by using 3 sources of capture-recapture (CRC) in Iran.Methods: This was a cross-sectional study ...
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Background: Cancer is the third cause of death in Iran. Oncologists play a key role in declining the mortality rate of cancer.Objectives: This study aims to accurately estimate oncologists’ active supply by using 3 sources of capture-recapture (CRC) in Iran.Methods: This was a cross-sectional study in 2015 targeting all oncologists in Iran registered in 3 independent sources, a hospitals national survey (213), database of Iran ministry of health and medical education (180), and the database of continuing medical education (173) were used to identify number of oncologists that were active. Duplicate records between the 3 sources were identified and removed using the Microsoft Office Access software. Medical council codes, names, surnames, as well as national ID codes were used for data linkage between the 3 sources.Results: After removing the duplicate records, a total of 314 oncologists were identified. Based on the selected model, it was estimated that the total number of oncologists were 533 in 2015. They included 325 adult hematologist-oncologists, followed by 88 pediatric oncologists, 47 surgical oncologists, 20 gynecologic oncologists, and 18 urologic oncologists. The estimated ratios for oncologist to population and oncologist to patients suffering from cancer were 0.67 and 1.34 per 100,000, respectively. Completeness of data for all 3 data sources after removing duplicates was 59.13%.Conclusions: This study highlighted the shortage of oncologists in Iran and showed that the quality of Iran specialists’ registration databases needs improvement.
